Danvers, Boston.
ACTA2 Alliance was founded in 2018 with a clear purpose: to bring together a community that, until then, had been scattered across countries and continents.
In 2019, that vision became reality with the MSMDS-ACTA2 International Conference, the first global event dedicated entirely to this condition.
Since then, these biannual conferences have grown into a key moment for the community, bringing together families, clinicians, and researchers to share knowledge, connect, and move forward together.
The 2025 MSMDS-ACTA2 International Conference marked a new milestone for the community, reflecting how it has evolved from a small gathering into a connected international community.
Beyond these numbers, the conference strengthened connections across the community and welcomed new volunteers committed to moving the work forward.
Clinical Guidelines & Recommendations in MSMDS, Dr. Patricia Musolino, MD (MGH)
Advances in Research, Dr. Patricia Musolino, MD, PhD (MGH)
Advances in Research, Dr. Dianna Milewicz, MD, PhD (UT Health Houston)
Managing Difficult Behaviors: Principles for Home (Dr. Joseph N. Ricciardi PsyD, BCBA-D, CBIST)
The MSMDS-ACTA2 Conference is where the community comes together.
Families share their experiences, researchers listen and learn directly from patients, and new collaborations begin.
For many, it is the first time meeting others facing the same diagnosis, a moment that changes how they understand the journey ahead. What starts during these days continues long after, strengthening the community and helping shape the future of research and care.
And with each new conference, that momentum continues to grow, bringing more people together and moving the community one step further.
*This content is not intended as a substitute for professional medical advice, diagnosis, or treatment. Should you require medical advice, please contact a qualified medical professional who is familiar with Multisystemic Smooth Muscle Dysfunction Syndrome.
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